3RO9
Candida glabrata dihydrofolate reductase complexed with NADPH and 6-ethyl-5-[(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP1006)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Strain CBS138 chromosome J complete sequence | polymer | 225 | 26209.1 | 2 | UniProt (Q6FPH0) Pfam (PF00186) In PDB | Candida glabrata (yeast) | |
2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
3 | A, B | 6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine | non-polymer | 373.5 | 2 | Chemie (06U) | |||
4 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 217 (UniProt: Q6FPH0)
PDB | External Database | Details |
---|---|---|
Leu 218 | - | expression tag |
Glu 219 | - | expression tag |
His 220 | - | expression tag |
His 221 | - | expression tag |
His 222 | - | expression tag |
His 223 | - | expression tag |
His 224 | - | expression tag |
His 225 | - | expression tag |
His 226 | - | expression tag |
His 227 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 52418.1 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 2237.7 | |
All* | Total formula weight | 54655.9 |