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3RJI

Ternary complex of DNA Polymerase Beta with a gapped DNA containing 8odG at template position paired with non-hydrolyzable dCTP analog (dCMP(CF2)PP)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
2B
(T)
DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164860.11
3C
(P)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3')polymer103085.01
4D
(D)
DNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01
5E
(A)
2'-deoxy-5'-O-[(S)-{difluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]cytidinenon-polymer501.21Chemie (6CF)
6F, G
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
7H, I
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
8J, K
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
9L, M, N, O
(A, T, P, D)
waterwater18.0342Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47722.9
Non-Polymers*Number of molecules7
Total formula weight666.7
All*Total formula weight48389.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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