3RIB

Human lysine methyltransferase Smyd2 in complex with AdoHcy

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	N-lysine methyltransferase SMYD2	polymer	441	50831.2	2	UniProt (Q9NRG4) Pfam (PF00856) Pfam (PF01753) In PDB	Homo sapiens (human)	HSKM-B, Histone methyltransferase SMYD2, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2
2	A, B	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	A, B	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
4	A, B	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
5		water	water		18.0	49	Chemie (HOH)

Sequence modifications

A, B: 1 - 433 (UniProt: Q9NRG4)

PDB	External Database	Details
Leu 434	-	expression tag
Glu 435	-	expression tag
His 436	-	expression tag
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag
His 440	-	expression tag
His 441	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	101662.5
Non-Polymers*	Number of molecules	17
	Total formula weight	2025.8
All*	Total formula weight	103688.3

*Water molecules are not included.