3RHR
Crystal structure of the C707A mutant of the C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE in complex with NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Aldehyde dehydrogenase 1 family, member L1 | polymer | 517 | 56589.5 | 4 | UniProt (Q5HZB2) Pfam (PF00171) UniProt (by SIFTS) (P28037) | Rattus norvegicus (brown rat rat rats) | |
| 2 | E, FA, O, W (A, D, B, C) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 4 | Chemie (NDP) | |||
| 3 | AA, BA, CA, DA, F... (C, A, D, B) | SULFATE ION | non-polymer | 96.1 | 28 | Chemie (SO4) | |||
| 4 | EA, N, NA, V (C, A, D, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | OA, PA, QA, RA (A, B, C, D) | water | water | 18.0 | 1765 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 397 - 902 (UniProt: Q5HZB2)
| PDB | External Database | Details |
|---|---|---|
| Met 386 | - | expression tag |
| Arg 387 | - | expression tag |
| Gly 388 | - | expression tag |
| Ser 389 | - | expression tag |
| His 390 | - | expression tag |
| His 391 | - | expression tag |
| His 392 | - | expression tag |
| His 393 | - | expression tag |
| His 394 | - | expression tag |
| Thr 395 | - | expression tag |
| Thr 396 | - | expression tag |
| Ala 707 | Cys 707 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 226357.9 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 6039.8 | |
| All* | Total formula weight | 232397.8 |
