3RHM

Crystal structure of the E673Q mutant oF C-Terminal domain of 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Aldehyde dehydrogenase 1 family, member L1	polymer	517	56620.6	4	UniProt (Q5HZB2) Pfam (PF00171) UniProt (by SIFTS) (P28037)	Rattus norvegicus (brown rat rat rats)
2	AA, BA, CA, E, EA... (C, A, D, B)	SULFATE ION	non-polymer		96.1	28	Chemie (SO4)
3	DA, JA, M, U (C, D, A, B)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
4	KA, LA, MA, NA (A, B, C, D)	water	water		18.0	683	Chemie (HOH)

Sequence modifications

A, B, C, D: 397 - 902 (UniProt: Q5HZB2)

PDB	External Database	Details
Met 386	-	expression tag
Arg 387	-	expression tag
Gly 388	-	expression tag
Ser 389	-	expression tag
His 390	-	expression tag
His 391	-	expression tag
His 392	-	expression tag
His 393	-	expression tag
His 394	-	expression tag
Thr 395	-	expression tag
Thr 396	-	expression tag
Gln 673	Glu 673	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	226482.2
Non-Polymers*	Number of molecules	32
	Total formula weight	3058.1
All*	Total formula weight	229540.4

*Water molecules are not included.