3RGQ
Crystal Structure of PTPMT1 in complex with PI(5)P
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein-tyrosine phosphatase mitochondrial 1 | polymer | 156 | 17782.6 | 1 | UniProt (Q66GT5) Pfam (PF00782) | Mus musculus (mouse) | PTEN-like phosphatase, Phosphoinositide lipid phosphatase |
| 2 | B (A) | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate | non-polymer | 554.4 | 1 | Chemie (5P5) | |||
| 3 | C (A) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 104 - 259 (UniProt: Q66GT5)
| PDB | External Database | Details |
|---|---|---|
| Ser 200 | Cys 132 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17782.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 554.4 | |
| All* | Total formula weight | 18336.9 |
