3R8V
CDK2 in complex with inhibitor RC-1-135
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cyclin-dependent kinase 2 | polymer | 306 | 34761.3 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | CDK2, Cell division protein kinase 2, p33 protein kinase |
| 2 | A | [4-amino-2-(prop-2-en-1-ylamino)-1,3-thiazol-5-yl](3-nitrophenyl)methanone | non-polymer | 304.3 | 1 | Chemie (Z62) | |||
| 3 | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Pro -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34761.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 304.3 | |
| All* | Total formula weight | 35065.7 |
