3R7N

Caspase-2 bound with two copies of Ac-DVAD-CHO

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Caspase-2 subunit p18	polymer	160	18093.5	2	UniProt (P42575) Pfam (PF00656) In PDB	Homo sapiens (human)
2	B, D	Caspase-2 subunit p12	polymer	112	12921.0	2	UniProt (P42575) Pfam (PF00656) In PDB	Homo sapiens (human)
3	F, E	Peptide Inhibitor (ACE)DVAD-CHO	polymer	5	428.4	2	BIRD (PRD_001052)
4		water	water		18.0	212	Chemie (HOH)

Sequence modifications

A, C: 175 - 333 (UniProt: P42575)

PDB	External Database	Details
Met 174	-	EXPRESSION TAG

B, D: 349 - 452 (UniProt: P42575)

PDB	External Database	Details
Leu 453	-	EXPRESSION TAG
Glu 454	-	EXPRESSION TAG
His 455	-	EXPRESSION TAG
His 456	-	EXPRESSION TAG
His 457	-	EXPRESSION TAG
His 458	-	EXPRESSION TAG
His 459	-	EXPRESSION TAG
His 460	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	62885.9
All*	Total formula weight	62885.9

*Water molecules are not included.