3R6C

Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS179)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Anthranilate phosphoribosyltransferase	polymer	377	38717.7	2	UniProt (P66992) Pfam (PF02885) Pfam (PF00591) UniProt (by SIFTS) (P9WFX5) In PDB	Mycobacterium tuberculosis
2	A, B	1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose	non-polymer		390.1	2	Chemie (PRP)
3	A, B	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	A, B	8-methoxyphenanthro[3,4-d][1,3]dioxole-5,6-dicarboxylic acid	non-polymer		340.3	3	Chemie (17N)
5	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6		water	water		18.0	572	Chemie (HOH)

Sequence modifications

A, B: 2 - 370 (UniProt: P66992)

PDB	External Database	Details
Leu 371	-	expression tag
Glu 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77435.4
Non-Polymers*	Number of molecules	10
	Total formula weight	1990.3
All*	Total formula weight	79425.7

*Water molecules are not included.