3R6C
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS179)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Anthranilate phosphoribosyltransferase | polymer | 377 | 38717.7 | 2 | UniProt (P66992) Pfam (PF02885) Pfam (PF00591) UniProt (by SIFTS) (P9WFX5) | Mycobacterium tuberculosis | |
| 2 | C, H (A, B) | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 2 | Chemie (PRP) | |||
| 3 | D, E, I, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | F, G, K (A, B) | 8-methoxyphenanthro[3,4-d][1,3]dioxole-5,6-dicarboxylic acid | non-polymer | 340.3 | 3 | Chemie (17N) | |||
| 5 | L (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 572 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 370 (UniProt: P66992)
| PDB | External Database | Details |
|---|---|---|
| Leu 371 | - | expression tag |
| Glu 372 | - | expression tag |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77435.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1990.3 | |
| All* | Total formula weight | 79425.7 |
