3R5K
A designed redox-controlled caspase-7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Caspase-7 | polymer | 312 | 35456.0 | 2 | UniProt (P55210) Pfam (PF00656) | Homo sapiens (human) | CASP-7, Apoptotic protease Mch-3, CMH-1, ICE-like apoptotic protease 3, ICE-LAP3, Caspase-7 subunit p20, Caspase-7 subunit p11 |
| 2 | C, D, E, F, G... (A, B) | FORMIC ACID | non-polymer | 46.0 | 6 | Chemie (FMT) | |||
| 3 | I, J (A, B) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 303 (UniProt: P55210)
| PDB | External Database | Details |
|---|---|---|
| Met 196 | - | expression tag |
| Cys 210 | Arg 210 | engineered mutation |
| Ser 246 | Cys 246 | engineered mutation |
| Leu 304 | - | expression tag |
| Glu 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
| His 308 | - | expression tag |
| His 309 | - | expression tag |
| His 310 | - | expression tag |
| His 311 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70912.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 276.1 | |
| All* | Total formula weight | 71188.2 |
