3R5I
Crystal structure of liganded Hemoglobin complexed with a potent Antisickling agent, INN-312
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Hemoglobin subunit alpha | polymer | 141 | 15150.4 | 2 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (human) | Alpha-globin, Hemoglobin alpha chain |
| 2 | B, D (B, D) | Hemoglobin subunit beta | polymer | 146 | 15890.2 | 2 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (human) | Beta-globin, Hemoglobin beta chain, LVV-hemorphin-7 |
| 3 | E, I, M, P (A, B, C, D) | OXYGEN MOLECULE | non-polymer | 32.0 | 4 | Chemie (OXY) | |||
| 4 | F, J, N, Q (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 5 | G, H, O (A, C) | 5-methoxy-2-(pyridin-3-ylmethoxy)benzaldehyde | non-polymer | 243.3 | 3 | Chemie (3R5) | |||
| 6 | K, L, R (B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 309 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62081.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3611.9 | |
| All* | Total formula weight | 65693.0 |
