3R2X
Crystal structure of the de novo designed binding protein HB36.3 in complex the the 1918 influenza virus hemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemagglutinin | polymer | 331 | 36452.8 | 1 | UniProt (Q9WFX3) Pfam (PF00509) | Influenza A virus | 1918 hemagglutinin receptor binding domain |
| 2 | B (B) | Hemagglutinin | polymer | 179 | 20394.4 | 1 | UniProt (Q9WFX3) Pfam (PF00509) | Influenza A virus | 1918 hemagglutinin fusion subunit |
| 3 | C (C) | HB36.3, designed hemagglutinin binding protein | polymer | 93 | 10605.2 | 1 | artificial gene | ||
| 4 | D (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 5 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 11 - 329 (UniProt: Q9WFX3)
B: 1 - 176 (UniProt: Q9WFX3)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 177 | - | expression tag |
| Gly 178 | - | expression tag |
| Arg 179 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67452.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 68422.3 |
