3R2A
Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 and antagonist rhein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Retinoic acid receptor RXR-alpha | polymer | 240 | 26856.0 | 4 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1 |
| 2 | E, F (E, F) | Nuclear receptor corepressor 2 | polymer | 16 | 1749.2 | 2 | UniProt (Q9Y618) | Homo sapiens | SMRT, N-CoR2, CTG repeat protein 26, SMAP270, Silencing mediator of retinoic acid and thyroid hormone receptor, T3 receptor-associating factor, TRAC, thyroid-receptor-associated corepressor, retinoic-acid-receptor-associated corepressor |
| 3 | G, H (A, C) | 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid | non-polymer | 284.2 | 2 | Chemie (RHN) | |||
| 4 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 110922.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 568.4 | |
| All* | Total formula weight | 111490.9 |
