3R1K

Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis H37Rv in complex with CoA and an acetamide moiety

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Enhanced intracellular survival protein	polymer	428	46692.9	1	UniProt (P71727) Pfam (PF13527) Pfam (PF17668) Pfam (PF13530) UniProt (by SIFTS) (P9WFK7)	Mycobacterium tuberculosis
2	B (A)	COENZYME A	non-polymer		767.5	1	Chemie (COA)
3	C (A)	ACETAMIDE	non-polymer		59.1	1	Chemie (ACM)
4	D (A)	water	water		18.0	291	Chemie (HOH)

Sequence modifications

A: 2 - 402 (UniProt: P71727)

PDB	External Database	Details
Met -25	-	expression tag
Gly -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Leu -12	-	expression tag
Val -11	-	expression tag
Pro -10	-	expression tag
Arg -9	-	expression tag
Gly -8	-	expression tag
Ser -7	-	expression tag
His -6	-	expression tag
Met -5	-	expression tag
Leu -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asp -1	-	expression tag
Ser 0	-	expression tag
Met 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	46692.9
Non-Polymers*	Number of molecules	2
	Total formula weight	826.6
All*	Total formula weight	47519.5

*Water molecules are not included.