3R0T
Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-5279
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Casein kinase II subunit alpha | polymer | 337 | 40240.9 | 1 | UniProt (P68400) Pfam (PF00069) | Homo sapiens (human) | CK II alpha |
| 2 | B (A) | 3-(cyclopropylamino)-5-{[3-(trifluoromethyl)phenyl]amino}pyrimido[4,5-c]quinoline-8-carboxylic acid | non-polymer | 439.4 | 1 | Chemie (FU9) | |||
| 3 | C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | H, I, J, K, L... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 6 | Q (A) | water | water | 18.0 | 334 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40240.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1488.4 | |
| All* | Total formula weight | 41729.3 |
