3QZ1
Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Steroid 21-hydroxylase | polymer | 496 | 56160.3 | 4 | UniProt (P00191) Pfam (PF00067) | Bos taurus (bovine cow domestic cattle domestic cow) | 21-OHase, Cytochrome P-450c21, Cytochrome P450 21, Cytochrome P450 XXI, Cytochrome P450-C21 |
| 2 | E, H, K, N (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 3 | F, G, I, J, L... (A, B, C, D) | (9beta)-17-hydroxypregn-4-ene-3,20-dione | non-polymer | 330.5 | 8 | Chemie (3QZ) | |||
| 4 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 496 (UniProt: P00191)
| PDB | External Database | Details |
|---|---|---|
| Arg 241 | Thr 241 | engineered mutation |
| Ala 442 | Leu 442 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 224641.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5109.6 | |
| All* | Total formula weight | 229750.7 |
