3QZ1
Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Steroid 21-hydroxylase | polymer | 496 | 56160.3 | 4 | UniProt (P00191) Pfam (PF00067) | Bos taurus (bovine cow domestic cattle domestic cow) | 21-OHase, Cytochrome P-450c21, Cytochrome P450 21, Cytochrome P450 XXI, Cytochrome P450-C21 |
| 2 | E, H, K, N (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 3 | F, G, I, J, L... (A, B, C, D) | (9beta)-17-hydroxypregn-4-ene-3,20-dione | non-polymer | 330.5 | 8 | Chemie (3QZ) PubChem (16395880) PubChem (16758149) PubChem (16759250) PubChem (18530261) PubChem (6238) PubChem (71200612) PubChem (25762896) PubChem (29933816) PubChem (51410580) PubChem (1778808) PubChem (1778810) PubChem (1778806) PubChem (719694) PubChem (928565) PubChem (101793) PubChem (521928) PubChem (7076389) PubChem (124903235) PubChem (6603871) PubChem (6710628) PubChem (6918981) PubChem (7059644) PubChem (7076390) PubChem (7076391) PubChem (12624853) PubChem (124303825) PubChem (11872725) PubChem (11872726) PubChem (11872727) PubChem (12624852) PubChem (135012703) PubChem (138107689) PubChem (145875049) PubChem (166992003) PubChem (172011994) | |||
| 4 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 496 (UniProt: P00191)
| PDB | External Database | Details |
|---|---|---|
| Arg 241 | Thr 241 | engineered mutation |
| Ala 442 | Leu 442 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 224641.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5109.6 | |
| All* | Total formula weight | 229750.7 |
