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3QWW

Crystal structure of histone lysine methyltransferase SmyD2 in complex with the methyltransferase inhibitor sinefungin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
SET and MYND domain-containing protein 2polymer43349642.01UniProt (Q8R5A0)
Pfam (PF00856)
Pfam (PF01753)
Mus musculus (mouse)
2B
(A)
SINEFUNGINnon-polymer381.41Chemie (SFG)
3C, D, E
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
4F
(A)
waterwater18.0429Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight49642.0
Non-Polymers*Number of molecules4
Total formula weight577.6
All*Total formula weight50219.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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