3QW7
Crystal structure of the protease domain of Botulinum Neurotoxin Serotype A with a peptide inhibitor RRFC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Botulinum neurotoxin type A | polymer | 430 | 49415.7 | 1 | UniProt (A5HZZ9) Pfam (PF01742) UniProt (by SIFTS) (P0DPI1) In PDB | Clostridium botulinum | BoNT/A, Bontoxilysin-A, BOTOX |
| 2 | B | inhibitory peptide RRFC | polymer | 5 | 580.7 | 1 | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | water | water | 18.0 | 395 | Chemie (HOH) |
Sequence modifications
A: 1 - 424 (UniProt: A5HZZ9)
| PDB | External Database | Details |
|---|---|---|
| His 425 | - | expression tag |
| His 426 | - | expression tag |
| His 427 | - | expression tag |
| His 428 | - | expression tag |
| His 429 | - | expression tag |
| His 430 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49996.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 376.6 | |
| All* | Total formula weight | 50373.0 |
