3QTZ
CDK2 in complex with inhibitor RC-2-36
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-dependent kinase 2 | polymer | 306 | 34761.3 | 1 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | CDK2, Cell division protein kinase 2, p33 protein kinase |
| 2 | B, C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D (A) | 4-{[4-amino-5-(3-fluorobenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide | non-polymer | 392.4 | 1 | Chemie (X42) | |||
| 4 | E (A) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Pro -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34761.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 516.6 | |
| All* | Total formula weight | 35277.9 |
