3QTO
Thrombin Inhibition by Pyridin Derivatives
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Thrombin light chain | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (I) | Hirudin variant-2 | polymer | 13 | 1662.7 | 1 | UniProt (P09945) | Hirudo medicinalis | |
| 4 | D (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E (H) | D-phenylalanyl-N-[(1-methylpyridinium-3-yl)methyl]-L-prolinamide | non-polymer | 367.5 | 1 | BIRD (PRD_001079) Chemie (10P) | |||
| 6 | F (H) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | G (H) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 8 | H, I (H) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 9 | J, K, L (L, H, I) | water | water | 18.0 | 366 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35539.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 821.7 | |
| All* | Total formula weight | 36361.2 |
