3QS6
Crystal structure of LeuT mutant F259V,I359Q bound to sodium and L-tryptophan
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Na(+):neurotransmitter symporter (Snf family) | polymer | 519 | 58044.4 | 1 | UniProt (O67854) Pfam (PF00209) In PDB | Aquifex aeolicus | |
| 2 | A | TRYPTOPHAN | non-polymer | 204.2 | 1 | Chemie (TRP) | |||
| 3 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | A | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 3 | Chemie (BOG) | |||
| 5 | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 1 - 513 (UniProt: O67854)
| PDB | External Database | Details |
|---|---|---|
| Val 259 | Phe 259 | engineered mutation |
| Gln 359 | Ile 359 | engineered mutation |
| Gly 514 | - | expression tag |
| Thr 515 | - | expression tag |
| Leu 516 | - | expression tag |
| Val 517 | - | expression tag |
| Pro 518 | - | expression tag |
| Arg 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58044.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1127.3 | |
| All* | Total formula weight | 59171.7 |
