3QQU
Cocrystal structure of unphosphorylated igf with pyrimidine 8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Insulin-like growth factor 1 receptor | polymer | 301 | 34348.4 | 4 | UniProt (P08069) Pfam (PF07714) | Homo sapiens (human) | Insulin-like growth factor I receptor, IGF-I receptor |
| 2 | E, F, G, H (A, B, C, D) | N~2~-[3-methoxy-4-(morpholin-4-yl)phenyl]-N~4~-(quinolin-3-yl)pyrimidine-2,4-diamine | non-polymer | 428.5 | 4 | Chemie (01P) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 985 - 1283 (UniProt: P08069)
| PDB | External Database | Details |
|---|---|---|
| Gly 983 | - | expression tag |
| Ser 984 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 137393.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1713.9 | |
| All* | Total formula weight | 139107.6 |
