3QQS

Anthranilate phosphoribosyltransferase (TRPD) from Mycobacterium tuberculosis (complex with inhibitor ACS172)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Anthranilate phosphoribosyltransferase	polymer	377	38717.7	4	UniProt (P66992) Pfam (PF02885) Pfam (PF00591) UniProt (by SIFTS) (P9WFX5) In PDB	Mycobacterium tuberculosis
2	A, B, C	1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose	non-polymer		390.1	3	Chemie (PRP)
3	A, B, C	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)
4	A, B, C, D	2,2'-iminodibenzoic acid	non-polymer		257.2	7	Chemie (17C)
5	D	DIPHOSPHATE	non-polymer		173.9	1	Chemie (DPO)
6		water	water		18.0	601	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 370 (UniProt: P66992)

PDB	External Database	Details
Leu 371	-	expression tag
Glu 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	154870.8
Non-Polymers*	Number of molecules	16
	Total formula weight	3266.4
All*	Total formula weight	158137.1

*Water molecules are not included.