3QQS
Anthranilate phosphoribosyltransferase (TRPD) from Mycobacterium tuberculosis (complex with inhibitor ACS172)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Anthranilate phosphoribosyltransferase | polymer | 377 | 38717.7 | 4 | UniProt (P66992) Pfam (PF02885) Pfam (PF00591) UniProt (by SIFTS) (P9WFX5) | Mycobacterium tuberculosis | |
| 2 | E, I, M (A, B, C) | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 3 | Chemie (PRP) | |||
| 3 | F, G, J, K, N (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 4 | H, L, O, P, Q... (A, B, C, D) | 2,2'-iminodibenzoic acid | non-polymer | 257.2 | 7 | Chemie (17C) | |||
| 5 | R (D) | DIPHOSPHATE | non-polymer | 173.9 | 1 | Chemie (DPO) | |||
| 6 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 601 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 370 (UniProt: P66992)
| PDB | External Database | Details |
|---|---|---|
| Leu 371 | - | expression tag |
| Glu 372 | - | expression tag |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 154870.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3266.4 | |
| All* | Total formula weight | 158137.1 |
