3QQN

The retinal specific CD147 Ig0 domain: from molecular structure to biological activity

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Basigin	polymer	137	15469.7	2	UniProt (P35613) Pfam (PF13927)	Homo sapiens (human)	5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF
2	C, D (A, B)	water	water		18.0	158	Chemie (HOH)

Sequence modifications

A, B: 2 - 117 (UniProt: P35613)

PDB	External Database	Details
Mse -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Mse 1	-	expression tag
Ile 45	Thr 66	SEE REMARK 999
Mse 46	Cys 67	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30939.4
All*	Total formula weight	30939.4

*Water molecules are not included.