3QNC

Crystal Structure of a Rationally Designed OXA-10 Variant Showing Carbapenemase Activity, OXA-10loop48

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Oxacillinase	polymer	244	27568.4	2	UniProt (Q7BNC2)	Escherichia coli	OXA-10loop48, OXA-10 laboratory variant
2	C, D, E, F, G... (A, B)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
3	I, J, K, L, M... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
4	O (A)	CARBON DIOXIDE	non-polymer		44.0	1	Chemie (CO2)
5	U, V (A, B)	water	water		18.0	543	Chemie (HOH)

Sequence modifications

A, B: 20 - 207 (UniProt: Q7BNC2)
A, B: 221 - 266 (UniProt: Q7BNC2)

PDB	External Database	Details
Tyr 208	-	insertion
Ser 209	-	insertion
Thr 210	-	insertion
Arg 211	-	insertion
Ile 212	-	insertion
Glu 213	-	insertion
Pro 217	-	insertion
Lys 218	-	insertion
Ile 219	-	insertion
Gly 220	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55136.8
Non-Polymers*	Number of molecules	18
	Total formula weight	1405.1
All*	Total formula weight	56541.9

*Water molecules are not included.