3QNA

Crystal structure of a 6-pyruvoyltetrahydropterin synthase homologue from Esherichia coli complexed sepiapterin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	6-carboxy-5,6,7,8-tetrahydropterin synthase	polymer	141	15932.2	6	UniProt (C6EJA7) In PDB	Escherichia coli	6-carboxyterahydropterin synthase, PTPS
2	A, B, C, D, E...	BIOPTERIN	non-polymer		237.2	6	Chemie (BIO)
3	A, B, C, D, E...	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
4		water	water		18.0	75	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 0 - 120 (UniProt: C6EJA7)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Ala 26	Cys 27	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	95593.1
Non-Polymers*	Number of molecules	12
	Total formula weight	1815.7
All*	Total formula weight	97408.8

*Water molecules are not included.