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3QN2

Structure-based design of a disulfide-linked oligomeric form of the Simian Virus 40 (SV40) large T antigen DNA binding domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ALarge T antigenpolymer13415326.61UniProt (P03070)
Pfam (PF02217)
In PDB
Simian virus 40 (SV40)LT, LT-AG
2ACITRATE ANIONnon-polymer189.11Chemie (FLC)
3waterwater18.0127Chemie (HOH)
Sequence modifications
A: 131 - 260 (UniProt: P03070)
PDBExternal DatabaseDetails
Gly 129-expression tag
Ser 130-expression tag
Cys 151Phe 151engineered mutation
Ala 216Cys 216engineered mutation
Cys 256Asp 256engineered mutation
Ser 261-expression tag
Ser 262-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight15326.6
Non-Polymers*Number of molecules1
Total formula weight189.1
All*Total formula weight15515.7
*Water molecules are not included.

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PDB entries from 2024-07-10

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