3QMK
Crystal structure of the E2 domain of APLP1 in complex with heparin hexasaccharide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Amyloid-like protein 1 | polymer | 214 | 24838.0 | 2 | UniProt (P51693) Pfam (PF12925) | Homo sapiens (human) | APLP, APLP-1, C30 |
| 2 | C (C) | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose | branched | 1173.0 | 1 | In PDB GlyTouCan (G35014IY) | |||
| 3 | D, E, F (B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A, B: 285 - 494 (UniProt: P51693)
| PDB | External Database | Details |
|---|---|---|
| Gly 281 | - | expression tag |
| Ser 282 | - | expression tag |
| His 283 | - | expression tag |
| Met 284 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49676.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1173.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 51137.2 |
