3QLU

Crystal structure of the GluK2/GluK5 (GluR6/KA2) ATD dimer assembly

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Glutamate receptor, ionotropic kainate 5	polymer	393	43798.2	2	UniProt (Q63273) Pfam (PF01094) In PDB	Rattus norvegicus (brown rat rat rats)	Glutamate receptor KA-2, KA2
2	C, D	Glutamate receptor, ionotropic kainate 2	polymer	395	44823.2	2	UniProt (P42260) Pfam (PF01094) In PDB	Rattus norvegicus (brown rat rat rats)	Glutamate receptor 6, GluR-6, GluR6
3	A, B, C, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	16	Chemie (NAG)
4	B, C	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6		water	water		18.0	6	Chemie (HOH)

Sequence modifications

A, B: 1 - 387 (UniProt: Q63273)

PDB	External Database	Details
Leu 388	-	expression tag
Glu 389	-	expression tag
Leu 390	-	expression tag
Val 391	-	expression tag
Pro 392	-	expression tag
Arg 393	-	expression tag

C, D: 1 - 389 (UniProt: P42260)

PDB	External Database	Details
Asn 213	Ala 244	engineered mutation
Ser 215	Gly 246	engineered mutation
Leu 390	-	expression tag
Glu 391	-	expression tag
Leu 392	-	expression tag
Val 393	-	expression tag
Pro 394	-	expression tag
Arg 395	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	177242.7
Non-Polymers*	Number of molecules	19
	Total formula weight	3702.3
All*	Total formula weight	180945.0

*Water molecules are not included.