3QLC
Complex structure of ATRX ADD domain bound to unmodified H3 1-15 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transcriptional regulator ATRX | polymer | 129 | 14793.9 | 2 | UniProt (P46100) Pfam (PF17981) | Homo sapiens (human) | ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX |
| 2 | C, D (C, D) | peptide of Histone H3.3 | polymer | 15 | 1565.8 | 2 | UniProt (P84243) | Homo sapiens | |
| 3 | E, F, G, H, I... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
A, B: 167 - 289 (UniProt: P46100)
| PDB | External Database | Details |
|---|---|---|
| Gly 161 | - | expression tag |
| Pro 162 | - | expression tag |
| Leu 163 | - | expression tag |
| Gly 164 | - | expression tag |
| Ser 165 | - | expression tag |
| Met 166 | - | expression tag |
| Arg 251 | Lys 251 | engineered mutation |
| Tyr 284 | Phe 284 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 32719.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 392.5 | |
| All* | Total formula weight | 33111.8 |
