3QKZ
Crystal structure of mutant His269Arg AKR1B14
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aldo-keto reductase family 1, member B7 | polymer | 316 | 36192.8 | 2 | UniProt (Q5RJP0) Pfam (PF00248) | Rattus norvegicus (rat) | RCG28223, isoform CRA_a |
| 2 | C, D (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 657 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 316 (UniProt: Q5RJP0)
| PDB | External Database | Details |
|---|---|---|
| Arg 269 | His 269 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72385.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1486.8 | |
| All* | Total formula weight | 73872.4 |
