3QKQ
Protein Tyrosine Phosphatase 1B - W179F mutant bound with vanadate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 321 | 37326.6 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase 1B, PTP-1B |
| 2 | B (A) | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) | |||
| 3 | C (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 4 | D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | G (A) | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Phe 179 | Trp 179 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37326.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 513.4 | |
| All* | Total formula weight | 37840.0 |
