3QIW
Crystal structure of the 226 TCR in complex with MCC-p5E/I-Ek
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain | polymer | 192 | 22361.1 | 1 | UniProt (P04224) Pfam (PF00993) Pfam (PF07654) In PDB | Mus musculus (mouse) | |
| 2 | B | MHC CLASS II H2-IA-BETA CHAIN | polymer | 196 | 22972.6 | 1 | UniProt (Q31163) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P04230) In PDB | Mus musculus (mouse) | |
| 3 | C | TCR 226 alpha chain | polymer | 205 | 22822.3 | 1 | Manduca sexta (Carolina sphinx hornblower tobacco hawkmoth tomato hornworm) | ||
| 4 | D | TCR 226 beta chain | polymer | 243 | 27613.9 | 1 | Mus musculus (mouse) | ||
| 5 | E | MCC-p5E peptide | polymer | 13 | 1393.6 | 1 | UniProt (P00039) In PDB | Mus musculus (mouse) | |
| 6 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
E: 2 - 13 (UniProt: P00039)
| PDB | External Database | Details |
|---|---|---|
| Glu 9 | Lys 104 | engineered mutation |
| Gly 14 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 97163.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 97605.8 |
