3QIN
Crystal Structure of HIV-1 RNase H p15 with engineered E. coli loop and pyrimidinol carboxylic acid inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Fusion protein of HIV-1 RNase H p15 with engineered E. coli loop | polymer | 150 | 16921.5 | 1 | UniProt (P04585) UniProt (P0A7Y4) Pfam (PF00075) In PDB | Human immunodeficiency virus type 1 group M subtype B (HIV-1) | Pr160Gag-Pol,RNase HI,Ribonuclease H,RNase H |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | A | 2-(3-bromo-4-methoxybenzyl)-5,6-dihydroxypyrimidine-4-carboxylic acid | non-polymer | 355.1 | 1 | Chemie (P1Y) | |||
| 5 | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A: 427 - 506 (UniProt: P04585)
A: 79 - 102 (UniProt: P0A7Y4)
A: 517 - 561 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Met 426 | - | initiating methionine |
A: 517 - 561 (UniProt: P04585)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16921.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 561.1 | |
| All* | Total formula weight | 17482.5 |
