3QFS

Crystal Structure of NADPH-Cytochrome P450 Reductase (FAD/NADPH domain)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	NADPH--cytochrome P450 reductase	polymer	458	52003.1	1	UniProt (P16435) Pfam (PF00667) Pfam (PF00175) In PDB	Homo sapiens (human)	CPR, P450R
2	A	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	1	Chemie (FAD)
3	A	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	1	Chemie (NAP)
4		water	water		18.0	424	Chemie (HOH)

Sequence modifications

A: 244 - 680 (UniProt: P16435)

PDB	External Database	Details
Met 223	-	expression tag
Gly 224	-	expression tag
Ser 225	-	expression tag
Ser 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag
Ser 233	-	expression tag
Ser 234	-	expression tag
Gly 235	-	expression tag
Leu 236	-	expression tag
Val 237	-	expression tag
Pro 238	-	expression tag
Arg 239	-	expression tag
Gly 240	-	expression tag
Ser 241	-	expression tag
His 242	-	expression tag
Met 243	-	expression tag
Val 503	Ala 500	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	52003.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1529.0
All*	Total formula weight	53532.0

*Water molecules are not included.