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3QEA

Crystal structure of human exonuclease 1 Exo1 (WT) in complex with DNA (complex II)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(Z)
Exonuclease 1polymer35239559.91UniProt (Q9UQ84)
Pfam (PF00752)
Pfam (PF00867)
Homo sapiens (human)hExo1, Exonuclease I, hExoI
2B
(A)
DNA (5'-D(P*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3')polymer133951.61
3C
(B)
DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3')polymer103045.01
4D, E, F, G
(Z)
BARIUM IONnon-polymer137.34Chemie (BA)
5H
(Z)
waterwater18.06Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight46556.5
Non-Polymers*Number of molecules4
Total formula weight549.3
All*Total formula weight47105.8
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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