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3QCX

Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 6-{2-Amino-6-[(3R)-3-methyl-4-morpholinyl]-4-pyrimidinyl}-1H-indazol-3-amine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
3-phosphoinositide-dependent protein kinase 1polymer31235652.91UniProt (O15530)
Pfam (PF00069)
Homo sapiens (human)hPDK1
2B, C, D, E, M
(A)
GLYCEROLnon-polymer92.15Chemie (GOL)
3F, G, H, I, J...
(A)
SULFATE IONnon-polymer96.16Chemie (SO4)
4L
(A)
6-{2-amino-6-[(3R)-3-methylmorpholin-4-yl]pyrimidin-4-yl}-2H-indazol-3-aminenon-polymer325.41Chemie (3Q2)
5N
(A)
waterwater18.049Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35652.9
Non-Polymers*Number of molecules12
Total formula weight1362.2
All*Total formula weight37015.1
*Water molecules are not included.

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PDB entries from 2025-12-03

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