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3QCS

Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 6-[2-Amino-6-(4-morpholinyl)-4-pyrimidinyl]-1H-indazol-3-amine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
3-phosphoinositide-dependent protein kinase 1polymer31235652.91UniProt (O15530)
Pfam (PF00069)
Homo sapiens (human)hPDK1
2B, C, D, E
(A)
GLYCEROLnon-polymer92.14Chemie (GOL)
3F, G, H, J, K
(A)
SULFATE IONnon-polymer96.15Chemie (SO4)
4I
(A)
6-[2-amino-6-(morpholin-4-yl)pyrimidin-4-yl]-2H-indazol-3-aminenon-polymer311.31Chemie (3Q1)
5L
(A)
waterwater18.020Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35652.9
Non-Polymers*Number of molecules10
Total formula weight1160.0
All*Total formula weight36812.9
*Water molecules are not included.

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PDB entries from 2025-12-24

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