3QCL
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1-yl)benzoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Receptor-type tyrosine-protein phosphatase gamma | polymer | 310 | 35705.5 | 1 | UniProt (P23470) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase gamma, R-PTP-gamma |
| 2 | B (A) | 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1-yl)benzoic acid | non-polymer | 381.3 | 1 | Chemie (NXV) | |||
| 3 | C (A) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A: 825 - 1128 (UniProt: P23470)
| PDB | External Database | Details |
|---|---|---|
| Gly 819 | - | expression tag |
| Ser 820 | - | expression tag |
| His 821 | - | expression tag |
| Met 822 | - | expression tag |
| Gly 823 | - | expression tag |
| Ser 824 | - | expression tag |
| Ser 858 | Cys 858 | engineered mutation |
| Thr 970 | Ser 970 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35705.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 381.3 | |
| All* | Total formula weight | 36086.8 |
