3QCF
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid via co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor-type tyrosine-protein phosphatase gamma | polymer | 310 | 35707.6 | 2 | UniProt (P23470) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase gamma, R-PTP-gamma |
| 2 | C, D (A, B) | 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid | non-polymer | 319.2 | 2 | Chemie (NXY) | |||
| 3 | E (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A, B: 825 - 1128 (UniProt: P23470)
| PDB | External Database | Details |
|---|---|---|
| Gly 819 | - | expression tag |
| Ser 820 | - | expression tag |
| His 821 | - | expression tag |
| Met 822 | - | expression tag |
| Gly 823 | - | expression tag |
| Ser 824 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71415.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 734.5 | |
| All* | Total formula weight | 72149.7 |
