3Q96

B-Raf kinase domain in complex with a tetrahydronaphthalene inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Serine/threonine-protein kinase B-raf	polymer	282	32150.2	2	UniProt (P15056) Pfam (PF07714) In PDB	Homo sapiens (human)	Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1
2	A, B	(2S)-N-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-7-[(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-4-yl)oxy]-1,2,3,4-tetrahydronaphthalene-2-carboxamide	non-polymer		538.6	2	Chemie (0NF)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64300.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1077.1
All*	Total formula weight	65377.6

*Water molecules are not included.