3Q7A
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Farnesyltransferase alpha subunit | polymer | 349 | 40913.2 | 1 | Cryptococcus neoformans | ||
| 2 | B (B) | Farnesyltransferase beta subunit | polymer | 520 | 56806.9 | 1 | Cryptococcus neoformans | ||
| 3 | C, D, E (C, D, E) | beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | branched | 342.3 | 3 | In PDB BIRD (PRD_900003) | sucrose | ||
| 4 | F (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | G, H, I (B) | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid | non-polymer | 237.3 | 3 | Chemie (3FX) | |||
| 6 | J (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | K (B) | FARNESYL DIPHOSPHATE | non-polymer | 382.3 | 1 | Chemie (FPP) | |||
| 8 | L (B) | 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE | non-polymer | 405.9 | 1 | Chemie (778) | |||
| 9 | M, N (A, B) | water | water | 18.0 | 721 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97720.1 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1026.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1661.6 | |
| All* | Total formula weight | 100408.6 |
