3Q5H
Clinically Useful Alkyl Amine Renin Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Renin | polymer | 340 | 37267.0 | 2 | UniProt (P00797) Pfam (PF00026) | Homo sapiens (human) | Angiotensinogenase |
| 2 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D, F, G, H, I... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) PubChem (312) | |||
| 4 | E, J (A, B) | methyl (2-{(R)-(3-chlorophenyl)[(3R)-1-({(2S)-1-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propan-2-yl}carbamoyl)piperidin-3-yl]methoxy}ethyl)carbamate | non-polymer | 525.1 | 2 | Chemie (RX6) PubChem (24849390) PubChem (24849391) PubChem (53497561) PubChem (58017387) PubChem (67363533) PubChem (67364517) PubChem (69262484) PubChem (70302237) PubChem (58017410) PubChem (147613837) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74534.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1262.9 | |
| All* | Total formula weight | 76221.3 |
