3Q4Z
Structure of unphosphorylated PAK1 kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase PAK 1 | polymer | 306 | 34514.7 | 2 | UniProt (Q13153) Pfam (PF00069) | Homo sapiens (human) | Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK |
| 2 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | D (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A, B: 248 - 545 (UniProt: Q13153)
| PDB | External Database | Details |
|---|---|---|
| Ile 259 | Ser 259 | engineered mutation |
| Arg 299 | Lys 299 | engineered mutation |
| Asn 389 | Asp 389 | engineered mutation |
| Ile 516 | Leu 516 | engineered mutation |
| Leu 546 | - | expression tag |
| Glu 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
| His 552 | - | expression tag |
| His 553 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69029.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 530.5 | |
| All* | Total formula weight | 69559.9 |
