3Q4B
Clinically Useful Alkyl Amine Renin Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Renin | polymer | 340 | 37267.0 | 2 | UniProt (P00797) Pfam (PF00026) | Homo sapiens (human) | Angiotensinogenase |
| 2 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | D, F, G, H, I... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) PubChem (312) | |||
| 4 | E, J (A, B) | methyl (2-{(R)-(3-chlorophenyl)[(3R)-1-({(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl}carbamoyl)piperidin-3-yl] methoxy}ethyl)carbamate | non-polymer | 525.1 | 2 | Chemie (RX5) PubChem (24812072) PubChem (53401325) PubChem (66577056) PubChem (66926232) PubChem (67104180) PubChem (87617525) PubChem (73014270) PubChem (97290366) PubChem (97305560) PubChem (98005951) PubChem (98005952) PubChem (98005953) PubChem (124583868) PubChem (16126898) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74534.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1484.1 | |
| All* | Total formula weight | 76018.1 |
