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3Q2Z

Human Squalene synthase in complex with N-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-neopentyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-acetyl]-L-aspartic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Squalene synthasepolymer34039166.71UniProt (P37268)
Pfam (PF00494)
Homo sapiens (human)SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase
2B
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
3C
(A)
N-{[(3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]acetyl}-L-aspartic acidnon-polymer577.01Chemie (D9A)
4D
(A)
waterwater18.0122Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39166.7
Non-Polymers*Number of molecules2
Total formula weight672.0
All*Total formula weight39838.7
*Water molecules are not included.

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PDB entries from 2025-12-03

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