3Q1E
Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 5-hydroxyisourate hydrolase | polymer | 119 | 13172.0 | 4 | UniProt (Q06S87) Pfam (PF00576) | Danio rerio (zebra fish) | HIU hydrolase, HIUHase, Transthyretin-related protein |
| 2 | E, F (C, D) | 3,5,3',5'-TETRAIODO-L-THYRONINE | non-polymer | 776.9 | 2 | Chemie (T44) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 119 (UniProt: Q06S87)
| PDB | External Database | Details |
|---|---|---|
| Ala 16 | Ile 35 | engineered mutation |
| Thr 116 | Tyr 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 52687.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1553.7 | |
| All* | Total formula weight | 54241.6 |
