3PX7
Crystal Structure of covalent complex of topoisomerase 1A with substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA topoisomerase | polymer | 595 | 67277.1 | 1 | UniProt (C9QXS7) Pfam (PF01751) Pfam (PF01131) UniProt (by SIFTS) (P06612) In PDB | Escherichia coli DH1 | |
| 2 | B | DNA 5'-D(*TP*TP*GP*GP*G)-3' | polymer | 5 | 1551.0 | 1 | |||
| 3 | C | DNA 5'-D(*A*AP*TP*GP*CP*GP*CP*T)-3' | polymer | 8 | 2426.6 | 1 | |||
| 4 | A, B, C | MERCURY (II) ION | non-polymer | 200.6 | 3 | Chemie (HG) | |||
| 5 | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A: 1 - 595 (UniProt: C9QXS7)
| PDB | External Database | Details |
|---|---|---|
| Asn 111 | Asp 111 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71254.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 601.8 | |
| All* | Total formula weight | 71856.6 |
