3PWY
Crystal structure of an extender (SPD28345)-modified human PDK1 complex 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3-phosphoinositide-dependent protein kinase 1 | polymer | 311 | 35459.8 | 1 | UniProt (O15530) Pfam (PF00069) | Homo sapiens (human) | hPDK1 |
| 2 | B (A) | N-[2-({6-[(2-sulfanylethyl)amino]pyrimidin-4-yl}amino)ethyl]propanamide | non-polymer | 269.4 | 1 | Chemie (SYP) |
Sequence modifications
A: 51 - 359 (UniProt: O15530)
| PDB | External Database | Details |
|---|---|---|
| Gly 49 | - | expression tag |
| Pro 50 | - | expression tag |
| Cys 166 | Glu 166 | engineered mutation |
| Ser 260 | Cys 260 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35459.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 269.4 | |
| All* | Total formula weight | 35729.1 |
