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3PWA

Structure of C126A mutant of Plasmodium falciparum triosephosphate isomerase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Triosephosphate isomerasepolymer24827965.72UniProt (Q07412)
Pfam (PF00121)
Plasmodium falciparumTIM, Triose-phosphate isomerase
2C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
3D, F
(A, B)
ACETATE IONnon-polymer59.02Chemie (ACT)
4E
(B)
SULFATE IONnon-polymer96.11Chemie (SO4)
5G, H
(A, B)
waterwater18.0491Chemie (HOH)
Sequence modifications
A, B: 1 - 248 (UniProt: Q07412)
PDBExternal DatabaseDetails
Ala 126Cys 126engineered mutation
Val 163Ala 163conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight55931.3
Non-Polymers*Number of molecules4
Total formula weight276.2
All*Total formula weight56207.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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